CXCR2 antagonist 3
Product Specifications
CAS Number
2647464-92-2
Target
CXCR, Others
Related Pathways
GPCR/G Protein, Others, Autophagy, Immunology/Inflammation
Bioactivity
CXCR2 antagonist 3 (compound 11h) is a highly effective inhibitor of CXC chemokine receptor 2 (CXCR2), displaying double-digit nanomolar potencies in inhibiting neutrophil infiltration into the air pouch. Additionally, it reduces neutrophil and MDSC infiltration while enhancing CD3+ T lymphocyte infiltration into Pan02 tumor tissues [1].
Smiles
OC1=C2C(=CC=C1NC(NC3=C(C)C(F)=CC=C3)=O)C=CCS2(=O)=O
Molecular Formula
C17H15FN2O4S
Molecular Weight
362.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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