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CXCR2 antagonist 3

Product Specifications

CAS Number

2647464-92-2

Target

CXCR|||Others

Related Pathways

GPCR/G Protein|||Others|||Autophagy|||Immunology/Inflammation

Bioactivity

CXCR2 antagonist 3 (compound 11h) is a highly effective inhibitor of CXC chemokine receptor 2 (CXCR2), displaying double-digit nanomolar potencies in inhibiting neutrophil infiltration into the air pouch. Additionally, it reduces neutrophil and MDSC infiltration while enhancing CD3+ T lymphocyte infiltration into Pan02 tumor tissues [1].

Smiles

OC1=C2C(=CC=C1NC(NC3=C(C)C(F)=CC=C3)=O)C=CCS2(=O)=O

Molecular Formula

C17H15FN2O4S

Molecular Weight

362.38

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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