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APX2039

Product Specifications

CAS Number

2342606-49-7

Target

Antifungal

Related Pathways

Microbiology/Virology

Purity

0.9907

Bioactivity

APX2039 is an orally active fungal Gwt1 enzyme inhibitor and a prodrug of the novel Gwt2096 inhibitor APX1.APX2039 exhibits potent anti-Kryptococcal activity against C. neoformans and C. gattii.APX2039 exhibits potent antifungal activity and blocks the localization of GPI (glycosylphosphatidylinositol) anchored cell wall mannoproteins. APX2039 has potent antifungal activity and blocks the localization of GPI (glycosylphosphatidylinositol) -anchored cell wall mannoproteins.APX2039 can be used to study cryptococcal meningitis (CM) .

Smiles

Nc1ncccc1-c1cc(Cc2ccc(Oc3cccc(F)n3)cc2)no1

Molecular Formula

C20H15FN4O2

Molecular Weight

362.36

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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