APX2039
Product Specifications
CAS Number
2342606-49-7
Target
Antifungal
Related Pathways
Microbiology/Virology
Purity
0.9907
Bioactivity
APX2039 is an orally active fungal Gwt1 enzyme inhibitor and a prodrug of the novel Gwt2096 inhibitor APX1.APX2039 exhibits potent anti-Kryptococcal activity against C. neoformans and C. gattii.APX2039 exhibits potent antifungal activity and blocks the localization of GPI (glycosylphosphatidylinositol) anchored cell wall mannoproteins. APX2039 has potent antifungal activity and blocks the localization of GPI (glycosylphosphatidylinositol) -anchored cell wall mannoproteins.APX2039 can be used to study cryptococcal meningitis (CM) .
Smiles
Nc1ncccc1-c1cc(Cc2ccc(Oc3cccc(F)n3)cc2)no1
Molecular Formula
C20H15FN4O2
Molecular Weight
362.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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