VO-OHPic
Product Specifications
CAS Number
675848-25-6
Target
Others, Autophagy, PTEN, Apoptosis
Related Pathways
Autophagy, Apoptosis, Others, PI3K/Akt/mTOR signaling
Bioactivity
VO-OHPic is a reversible, noncompetitive, and selective inhibitor of PTEN with an IC50 of 46 nM, effectively attenuating apoptosis, adverse cardiac remodeling, and the presence of pro-inflammatory M1 macrophages in models of doxorubicin-induced cardiomyopathy. Additionally, VO-OHPic inhibits autophagy [1] [2] [3].
Smiles
[O-][V]=O.OC(=O)c1ncccc1O.OC(=O)c1ncccc1O
Molecular Formula
C12H10N2O8V
Molecular Weight
361.16
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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