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LDHA/PDKs-IN-1

Product Specifications

CAS Number

2490699-40-4

Target

Others, PDK

Related Pathways

PI3K/Akt/mTOR signaling, Others

Bioactivity

LDHA/PDKs-IN-1 (compound 20e) is a highly effective dual inhibitor of PDKs and LDHA, with IC50 values of 0.8 μM and 0.15 μM, respectively. It significantly suppresses A549 cell proliferation (EC50 = 13.2 μM), reduces lactate formation, and enhances oxygen consumption, holding great promise for cancer research [1].

Smiles

O(CCN1CCN(C(=O)C2=CC=C(F)C=C2)CC1)C=3C(=O)C=COC3C

Molecular Formula

C19H21FN2O4

Molecular Weight

360.38

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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