LDHA/PDKs-IN-1
Product Specifications
CAS Number
2490699-40-4
Target
Others|||PDK
Related Pathways
PI3K/Akt/mTOR signaling|||Others
Bioactivity
LDHA/PDKs-IN-1 (compound 20e) is a highly effective dual inhibitor of PDKs and LDHA, with IC50 values of 0.8 ?M and 0.15 ?M, respectively. It significantly suppresses A549 cell proliferation (EC50 = 13.2 ?M), reduces lactate formation, and enhances oxygen consumption, holding great promise for cancer research [1].
Smiles
O(CCN1CCN(C(=O)C2=CC=C(F)C=C2)CC1)C=3C(=O)C=COC3C
Molecular Formula
C19H21FN2O4
Molecular Weight
360.38
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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