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Rucaparib hydrochloride

Product Specifications

CAS Number

773059-19-1

Target

PARP, Others

Related Pathways

Others, Chromatin/Epigenetic, DNA Damage/DNA Repair

Bioactivity

Rucaparib hydrochloride, also known as AG014699, is a powerful and orally active compound that inhibits PARP proteins including PARP-1, PARP-2, and PARP-3 with a Ki value of 1.4 nM for PARP1. Additionally, Rucaparib hydrochloride acts as a modest inhibitor of hexose-6-phosphate dehydrogenase (H6PD) . This compound shows potential in research for castration-resistant prostate cancer (CRPC) [1] [2] [3] [4].

Smiles

Cl.CNCc1ccc(cc1)-c1[nH]c2cc(F)cc3C(=O)NCCc1c23

Molecular Formula

C19H19ClFN3O

Molecular Weight

359.83

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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