Rucaparib hydrochloride
Product Specifications
CAS Number
773059-19-1
Target
PARP|||Others
Related Pathways
Others|||Chromatin/Epigenetic|||DNA Damage/DNA Repair
Bioactivity
Rucaparib hydrochloride, also known as AG014699, is a powerful and orally active compound that inhibits PARP proteins including PARP-1, PARP-2, and PARP-3 with a Ki value of 1.4 nM for PARP1. Additionally, Rucaparib hydrochloride acts as a modest inhibitor of hexose-6-phosphate dehydrogenase (H6PD) . This compound shows potential in research for castration-resistant prostate cancer (CRPC) [1] [2] [3] [4].
Smiles
Cl.CNCc1ccc(cc1)-c1[nH]c2cc(F)cc3C(=O)NCCc1c23
Molecular Formula
C19H19ClFN3O
Molecular Weight
359.83
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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