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JAK-2/3-IN-2

Product Specifications

CAS Number

2170398-48-6

Target

JAK, Others

Related Pathways

JAK/STAT signaling, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Others, Stem Cells, Angiogenesis

Bioactivity

JAK-2/3-IN-2 (Compound 3h) is a potent dual inhibitor of JAK2 and JAK3, exhibiting inhibitory activity with IC50 values of 23.85 nM and 18.9 nM against JAK2 and JAK3, respectively [1].

Smiles

C(C)N1N(C(=O)C(SC2=CC=C(C)C=C2)=C1C)C3=C(Cl)C=CC=C3

Molecular Formula

C19H19ClN2OS

Molecular Weight

358.89

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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