Immunoproteasome inhibitor 1
Product Specifications
CAS Number
2755772-63-3
Target
Others, Proteasome
Related Pathways
Ubiquitination, Proteases/Proteasome, Others
Bioactivity
Immunoproteasome inhibitor 1 is a highly potent and reversible inhibitor of both immunoproteasome and proteasome activity. It exhibits time-independent inhibitory effects on immunoproteasome subunits β5c, β1i, and β5i, with respective Ki values of 1.18 μM, 0.27 μM, and 1.91 μM. This compound shows promising potential for the treatment of select neoplastic diseases [1].
Smiles
O=C1C=2C(=CC(OC)=C(OC)C2)C=CN1C/C=C/C(NCCC(C)C)=O
Molecular Formula
C20H26N2O4
Molecular Weight
358.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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