HIV-1 inhibitor-30
Product Specifications
CAS Number
2132412-77-0
Target
Others, HIV Protease
Related Pathways
Microbiology/Virology, Proteases/Proteasome, Others
Bioactivity
HIV-1 inhibitor-30 (compound 10i) is a potent inhibitor of HIV-1, specifically targeting the RT DNA polymerase enzyme, showing strong antiretroviral activity with an EC50 value of 40 nM and an IC50 value of 80 nM. Moreover, it demonstrates significant effectiveness against seven NNRTI-resistant strains of HIV-1 (RT-K103N; RT-Y181C; RT-K103N, Y181C; RT-L100I, K103N; RT-Y188L; RT-K103N, G190A; RT-K103N, V108I), with IC50 values from 0.04 to 1.42 μM. This compound holds potential for AIDS research [1].
Smiles
C(C(NC=1C(Cl)=CN=CC1)=O)C=2C=3C(N(OCCCC)C2)=CC=CC3
Molecular Formula
C19H20ClN3O2
Molecular Weight
357.83
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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