PHA-665752

477575-56-7

C-Met/HGFR, Autophagy, Apoptosis, FGFR, VEGFR, Bcr-Abl

Tyrosine Kinase/Adaptors, Autophagy, Angiogenesis, Cytoskeletal Signaling, Apoptosis

0.9935

PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), >50-fold selectivity for c-Met than STKs or RTKs.

C(=C\1/C=2C(NC1=O)=CC=C(S(CC3=C(Cl)C=CC=C3Cl)(=O)=O)C2)\C4=C(C)C(C(=O)N5[C@@H](CN6CCCC6)CCC5)=C(C)N4

C32H34Cl2N4O4S

641.61

Ice Packs

-20°C