Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Vutiglabridin

Product Specifications

CAS Number

1800188-47-9

Target

ROS, PPAR, Others, Phosphatase, Antibacterial

Related Pathways

Others, Metabolism, Microbiology/Virology, DNA Damage/DNA Repair, Immunology/Inflammation

Purity

0.9907

Bioactivity

Vutiglabridin (HSG4112) is a novel and safe modulator of PON2, a racemic compound. vutiglabridin is an optimized structural analogue of Glabridin and is superior to Glabridin in terms of weight loss and chemical stability. vutiglabridin ameliorates mptp-induced neurodegeneration in Parkinson's disease mice by targeting mitochondrial paraoxonase-2. Vutiglabridin is a clinical phase 2 drug for the treatment of obesity and has therapeutic effects on p-mitochondrial PON2 in a PD model. vutiglabridin penetrates the brain, binds PON2, and restores 1-methyl-4-phenylpyridine (MPP*) -induced neuroblastoma in SH-SY5Y Vutiglabridin significantly attenuated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) -induced dyskinesia and dopaminergic neuronal damage in mice modeled with PD in mouse experiments.

Smiles

CC1(C)OC2=C(C3=C(CC(CO3)C4=C(O)C=C(OCC)C=C4)C=C2)CC1

Molecular Formula

C22H26O4

Molecular Weight

354.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

ANAPC13 (NM_001242374) Human Tagged ORF Clone
RG231545 10 µg

ANAPC13 (NM_001242374) Human Tagged ORF Clone

Sign In for Pricing
View Details
IkappaB-beta (Phospho Thr19) Polyclonal Antibody
MBS9458945-01 0.05 mL

IkappaB-beta (Phospho Thr19) Polyclonal Antibody

Sign In for Pricing
View Details
IkappaB-beta (Phospho Thr19) Polyclonal Antibody
MBS9458945-02 0.1 mL

IkappaB-beta (Phospho Thr19) Polyclonal Antibody

Sign In for Pricing
View Details
IkappaB-beta (Phospho Thr19) Polyclonal Antibody
MBS9458945-03 5x 0.1 mL

IkappaB-beta (Phospho Thr19) Polyclonal Antibody

Sign In for Pricing
View Details
Ypel3 sgRNA CRISPR Lentivector (Mouse) (Target 1)
K3355602 1.0 µg DNA

Ypel3 sgRNA CRISPR Lentivector (Mouse) (Target 1)

Sign In for Pricing
View Details
3-Methyl-4- (4-methylphenyl) -1H-pyrazol-5-amine
JWB18759-01 250 mg

3-Methyl-4- (4-methylphenyl) -1H-pyrazol-5-amine

Sign In for Pricing
View Details