CA224
Product Specifications
CAS Number
883561-04-4
Target
Apoptosis, Others, CDK
Related Pathways
Apoptosis, Others, Cell Cycle/Checkpoint
Bioactivity
CA224 (Compound 1), an orally active and selective Cdk4–cyclin D1 inhibitor, demonstrates an IC50 of 6.2 μM. It induces cell apoptosis and exhibits antitumor activity [1].
Smiles
C(CN(C(=O)C1=CC=C(C=C1)C2=CC=CC=C2)C)C=3C=4C(NC3)=CC=CC4
Molecular Formula
C24H22N2O
Molecular Weight
354.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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