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CDK1/Cyc B-IN-1

Product Specifications

CAS Number

2459916-56-2

Target

Others|||Apoptosis|||CDK

Related Pathways

Apoptosis|||Others|||Cell Cycle/Checkpoint

Bioactivity

CDK1/Cyc B-IN-1 (Compound 5) is a potent inhibitor of the CDK1/Cyc B complex with an IC50 value of 97 nM. This compound induces apoptosis and G2/M cell cycle arrest, halting cancer cell proliferation, and exhibits a wide-ranging cytotoxic effect on various cancer cell lines [1].

Smiles

S=C1N(C=2C(S1)=C(Cl)N=C(C)N2)C3=C(OC)C=C(OC)C=C3

Molecular Formula

C14H12ClN3O2S2

Molecular Weight

353.85

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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