Semagacestat
Product Specifications
CAS Number
425386-60-3
Target
Gamma-secretase, Beta Amyloid
Related Pathways
Proteases/Proteasome, Stem Cells, Neuroscience
Purity
0.999
Bioactivity
Semagacestat (LY450139) (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM) .
Smiles
CC(C)[C@H](O)C(=O)N[C@@H](C)C(=O)N[C@H]1c2ccccc2CCN(C)C1=O
Molecular Formula
C19H27N3O4
Molecular Weight
361.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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