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Semagacestat

Product Specifications

CAS Number

425386-60-3

Target

Gamma-secretase|||Beta Amyloid

Related Pathways

Proteases/Proteasome|||Stem Cells|||Neuroscience

Purity

0.999

Bioactivity

Semagacestat (LY450139) (LY450139) is a ?-secretase blocker for A?42/A?40/A?38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM) .

Smiles

CC(C)[C@H](O)C(=O)N[C@@H](C)C(=O)N[C@H]1c2ccccc2CCN(C)C1=O

Molecular Formula

C19H27N3O4

Molecular Weight

361.44

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/D23F76F2-2F3E-4F67-9D50-E17A2D4884DD/T6125

Available Sizes

Curated Selection

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