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AhR agonist 2

Product Specifications

Target

AhR, Aryl Hydrocarbon Receptor

Related Pathways

Immunology/Inflammation, Metabolism

Bioactivity

AhR agonist 2 is a triazolopyridine derivative and novel aryl hydrocarbon receptor (AhR) agonist with the advantages of being orally bioavailable and highly potent (EC50=0.03 nM), inducing rapid nuclear enrichment of the AhR and facilitating skin barrier repair for the treatment of psoriasis.

Smiles

BrC=1C=CC(=CC1)C=2N=C3C=CC(Br)=CN3N2

Molecular Formula

C12H7Br2N3

Molecular Weight

353.01

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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