Tepotinib
Product Specifications
CAS Number
1100598-32-0
Target
C-Met/HGFR|||Autophagy|||TAM Receptor|||Trk receptor
Related Pathways
Tyrosine Kinase/Adaptors|||Autophagy
Purity
0.9991
Bioactivity
Tepotinib (EMD-1214063) is a c-MET tyrosine kinase inhibitor (IC50=3 nM) that is selective, orally active, and ATP-competitive. Tepotinib has antitumor effect and is used in the treatment of non-small cell lung cancer.
Smiles
CN1CCC(COc2cnc(nc2)-c2cccc(Cn3nc(ccc3=O)-c3cccc(c3)C#N)c2)CC1
Molecular Formula
C29H28N6O2
Molecular Weight
492.57
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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