What is the catalog number for AChE/BChE/BACE-1-IN-1?

The catalog number for AChE/BChE/BACE-1-IN-1 is T61206.

What sizes are available for AChE/BChE/BACE-1-IN-1?

AChE/BChE/BACE-1-IN-1 is available in the following size(s): 25 mg, 50 mg, 100 mg.

How many pack sizes does AChE/BChE/BACE-1-IN-1 come in?

AChE/BChE/BACE-1-IN-1 is available in 3 different pack sizes.

Is AChE/BChE/BACE-1-IN-1 in stock?

AChE/BChE/BACE-1-IN-1 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures AChE/BChE/BACE-1-IN-1?

AChE/BChE/BACE-1-IN-1 is manufactured by Molfinity.

What is the estimated delivery time for AChE/BChE/BACE-1-IN-1?

Estimated delivery time for AChE/BChE/BACE-1-IN-1 is approximately 10 business day(s), depending on your location.

AChE/BChE/BACE-1-IN-1

Product Specifications

CAS Number

1321361-13-0

Target

Beta-Secretase, Cholinesterase (ChE), ROS Kinase, Others

Related Pathways

Others, Neuroscience, Tyrosine Kinase/Adaptors

Bioactivity

AChE/BChE/BACE-1-IN-1 (Compound 4k) is an orally active inhibitor that targets acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and β-site amyloid precursor protein cleaving enzyme 1 (BACE-1), with IC50 values of 0.058 μM, 0.082 μM, and 0.115 μM against hAChE, hBChE, and hBACE-1, respectively. It exhibits significant binding affinity with PAS-AChE, excellent blood-brain barrier permeability, potential disassembly of amyloid-beta (Aβ) aggregates, neuroprotective properties against Aβ-induced stress, and remarkable antioxidant capabilities [1].