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Metallo-?-lactamase-IN-5

Product Specifications

CAS Number

1417737-65-5

Target

Others|||Apoptosis|||Antibacterial

Related Pathways

Apoptosis|||Others|||Microbiology/Virology

Bioactivity

Metallo-?-lactamase-IN-5 (compound 5c) is a potent inhibitor of metallo-?-lactamases (MBLs), demonstrating inhibitory activity against MBLs NDM-1 and VIM-1. It effectively inhibits HUVECs with an IC50 value of 45 ?g/mL. Additionally, when combined with Imipenem, Metallo-?-lactamase-IN-5 exhibits synergistic antimicrobial activity [1].

Smiles

N(=O)(=O)C=1C2=C(C(O)=C(CN(CC3=CC=CC=C3)CC#N)C1)N=CC=C2

Molecular Formula

C19H16N4O3

Molecular Weight

348.36

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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