Metallo-?-lactamase-IN-5
Product Specifications
CAS Number
1417737-65-5
Target
Others|||Apoptosis|||Antibacterial
Related Pathways
Apoptosis|||Others|||Microbiology/Virology
Bioactivity
Metallo-?-lactamase-IN-5 (compound 5c) is a potent inhibitor of metallo-?-lactamases (MBLs), demonstrating inhibitory activity against MBLs NDM-1 and VIM-1. It effectively inhibits HUVECs with an IC50 value of 45 ?g/mL. Additionally, when combined with Imipenem, Metallo-?-lactamase-IN-5 exhibits synergistic antimicrobial activity [1].
Smiles
N(=O)(=O)C=1C2=C(C(O)=C(CN(CC3=CC=CC=C3)CC#N)C1)N=CC=C2
Molecular Formula
C19H16N4O3
Molecular Weight
348.36
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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