ICG-001
Product Specifications
CAS Number
780757-88-2
Target
Epigenetic Reader Domain, Apoptosis, Wnt/beta-catenin
Related Pathways
Cytoskeletal Signaling, Chromatin/Epigenetic, Stem Cells, Apoptosis
Purity
>99.99%
Bioactivity
ICG001 is a β-catenin/TCF-mediated transcription inhibitor that selectively blocks β-catenin/CBP interaction without interfering with β-catenin/p300 interaction. It specifically binds to CREB protein with an IC50 of 3 μM.
Smiles
Oc1ccc(C[C@@H]2N3[C@H](CN(Cc4cccc5ccccc45)C2=O)N(CCC3=O)C(=O)NCc2ccccc2)cc1
Molecular Formula
C33H32N4O4
Molecular Weight
548.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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