FLT3-IN-13
Product Specifications
Target
Others|||FLT|||Apoptosis|||Topoisomerase
Related Pathways
Tyrosine Kinase/Adaptors|||DNA Damage/DNA Repair|||Others|||Apoptosis|||Angiogenesis
Bioactivity
FLT3-IN-13 (compound 20) is a highly effective inhibitor targeting both topoisomerase II and FLT3 proteins in leukemic cells, with IC50 values of 2.26 ?M for both. It induces cell cycle arrest at the G2/M phase, promotes apoptosis, and displays considerable anticytotoxic activity specifically against leukemia [1].
Molecular Formula
C20H14N4O2
Molecular Weight
342.35
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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