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FLT3-IN-13

Product Specifications

Target

Others|||FLT|||Apoptosis|||Topoisomerase

Related Pathways

Tyrosine Kinase/Adaptors|||DNA Damage/DNA Repair|||Others|||Apoptosis|||Angiogenesis

Bioactivity

FLT3-IN-13 (compound 20) is a highly effective inhibitor targeting both topoisomerase II and FLT3 proteins in leukemic cells, with IC50 values of 2.26 ?M for both. It induces cell cycle arrest at the G2/M phase, promotes apoptosis, and displays considerable anticytotoxic activity specifically against leukemia [1].

Molecular Formula

C20H14N4O2

Molecular Weight

342.35

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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