THK-5105
Product Specifications
CAS Number
1374107-46-6
Target
Others, Microtubule Associated
Related Pathways
Cytoskeletal Signaling, Others
Bioactivity
THK-5105, an arylquinoline derivative, demonstrates high binding affinity for tau fibrils, protein aggregates, and tau-rich Alzheimer's disease (AD) brain homogenates, indicating its potential as a tau imaging PET (Positron Emission Tomography) probe with the radiolabeled version, 18F-THK-5105 [1].
Smiles
O(CC(CF)O)C1=CC2=C(N=C(C=C2)C3=CC=C(N(C)C)C=C3)C=C1
Molecular Formula
C20H21FN2O2
Molecular Weight
340.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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