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THK-5105

Product Specifications

CAS Number

1374107-46-6

Target

Others, Microtubule Associated

Related Pathways

Cytoskeletal Signaling, Others

Bioactivity

THK-5105, an arylquinoline derivative, demonstrates high binding affinity for tau fibrils, protein aggregates, and tau-rich Alzheimer's disease (AD) brain homogenates, indicating its potential as a tau imaging PET (Positron Emission Tomography) probe with the radiolabeled version, 18F-THK-5105 [1].

Smiles

O(CC(CF)O)C1=CC2=C(N=C(C=C2)C3=CC=C(N(C)C)C=C3)C=C1

Molecular Formula

C20H21FN2O2

Molecular Weight

340.39

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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