L-I-OddU
Product Specifications
CAS Number
207920-87-4
Target
Nucleoside Antimetabolite/Analog|||Antifection|||DNA/RNA Synthesis|||Others
Related Pathways
Cell Cycle/Checkpoint|||Microbiology/Virology|||Others|||DNA Damage/DNA Repair
Bioactivity
L-I-OddU, a potent and selective anti-Epstein-Barr virus (EBV) agent, is a L-5'-halo-dioxolane nucleoside analogue. It demonstrates antiviral activity by effectively suppressing replicative EBV DNA and viral protein synthesis [1] [2]. With an EC 50 value of 0.03 ?M, L-I-OddU exhibits high potency against EBV while maintaining low cytotoxicity, as indicated by its CC 50 value of 1000 nM.
Smiles
O=C1N([C@H]2O[C@@H](CO)OC2)C=C(I)C(=O)N1
Molecular Formula
C8H9IN2O5
Molecular Weight
340.07
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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