Type II topoisomerase inhibitor 1
Product Specifications
CAS Number
2245691-60-3
Target
Topoisomerase, Antibacterial, Others, DNA/RNA Synthesis
Related Pathways
Microbiology/Virology, Cell Cycle/Checkpoint, Others, DNA Damage/DNA Repair
Bioactivity
Type II topoisomerase inhibitor 1 is a potent and selective inhibitor of E. coli DNA gyrase with an IC50 value of 1.7 nM and forms hydrogen bonds with the Asp73 residue. It inhibits topoisomerase IV activity with an IC50 value of 0.98 μM and is applicable in the antibacterial area [1] [2].
Smiles
N(C)C1=C2C(C=C(C(NC3=CC=C(C(O)=O)C=C3)=O)C(=O)N2)=CC=C1
Molecular Formula
C18H15N3O4
Molecular Weight
337.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC040181-500 1x 500 µL
CD59 (heavy chain of Protectin) (BRA-10G), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC041283-100 1x 100 µL
VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/1283), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC681190-100 1x 100 µL
Cytokeratin 18 (KRT18/1190), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC942063-500 1x 500 µL
CD103 / Integrin alpha E (T-Cell Lymphoma & Hairy Cell Leukemia Marker) (ITGAE/2063), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details