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Cerdulatinib hydrochloride

Product Specifications

CAS Number

1369761-01-2

Target

C-Fms|||JAK|||MLK|||Hippo pathway|||Syk|||Tyrosine Kinases

Related Pathways

JAK/STAT signaling|||Chromatin/Epigenetic|||MAPK|||Stem Cells|||Tyrosine Kinase/Adaptors|||Angiogenesis

Purity

0.9985

Bioactivity

Cerdulatinib hydrochloride (PRT2070 hydrochloride) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk, respectively. Also inhibits 19 other tested kinases with IC50 less than 200 nM.

Smiles

Cl.CCS(=O)(=O)N1CCN(CC1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1

Molecular Formula

C20H28ClN7O3S

Molecular Weight

482

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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