Cerdulatinib hydrochloride
Product Specifications
CAS Number
1369761-01-2
Target
C-Fms, JAK, MLK, Hippo pathway, Syk, Tyrosine Kinases
Related Pathways
JAK/STAT signaling, Chromatin/Epigenetic, MAPK, Stem Cells, Tyrosine Kinase/Adaptors, Angiogenesis
Purity
0.9985
Bioactivity
Cerdulatinib hydrochloride (PRT2070 hydrochloride) is an oral active, multi-targeted tyrosine kinase inhibitor with IC50 of 12 nM/6 nM/8 nM/0.5 nM and 32 nM for JAK1/JAK2/JAK3/TYK2 and Syk, respectively. Also inhibits 19 other tested kinases with IC50 less than 200 nM.
Smiles
Cl.CCS(=O)(=O)N1CCN(CC1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1
Molecular Formula
C20H28ClN7O3S
Molecular Weight
482
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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