GL0388
Product Specifications
Target
Others, Bcl-2 Family
Related Pathways
Others, Apoptosis
Bioactivity
GL0388 is a Bax activator and leads to Bax insertion into mitochondrial membrane that induce Bax-mediated apoptosis. GL0388 inhibits tumor growth of breast cancer xenograft in vivo which also exhibits antiproliferative activities against a variety of cancer cells with IC50 values of 0.299-1.57 μM [1].
Molecular Formula
C21H17FN2O
Molecular Weight
332.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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