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GL0388

Product Specifications

Target

Others, Bcl-2 Family

Related Pathways

Others, Apoptosis

Bioactivity

GL0388 is a Bax activator and leads to Bax insertion into mitochondrial membrane that induce Bax-mediated apoptosis. GL0388 inhibits tumor growth of breast cancer xenograft in vivo which also exhibits antiproliferative activities against a variety of cancer cells with IC50 values of 0.299-1.57 μM [1].

Molecular Formula

C21H17FN2O

Molecular Weight

332.37

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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