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LDHA/PDKs-IN-2

Product Specifications

CAS Number

2490699-44-8

Target

Others, PDK

Related Pathways

Others, PI3K/Akt/mTOR signaling

Bioactivity

LDHA/PDKs-IN-2 (compound 20k) is a potent dual inhibitor of LDHA and PDKs, with IC50 values of 0.7 and 1.6 μM, respectively. It increases oxygen consumption, decreases lactate formation, and shows potential for cancer research by reducing the proliferation of A549 cells with an EC50 of 15.7 μM [1].

Smiles

C(=O)(N1CCN(CCOC=2C(=O)C=COC2C)CC1)C3=CC=CO3

Molecular Formula

C17H20N2O5

Molecular Weight

332.35

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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