LDHA/PDKs-IN-2
Product Specifications
CAS Number
2490699-44-8
Target
Others|||PDK
Related Pathways
Others|||PI3K/Akt/mTOR signaling
Bioactivity
LDHA/PDKs-IN-2 (compound 20k) is a potent dual inhibitor of LDHA and PDKs, with IC50 values of 0.7 and 1.6 ?M, respectively. It increases oxygen consumption, decreases lactate formation, and shows potential for cancer research by reducing the proliferation of A549 cells with an EC50 of 15.7 ?M [1].
Smiles
C(=O)(N1CCN(CCOC=2C(=O)C=COC2C)CC1)C3=CC=CO3
Molecular Formula
C17H20N2O5
Molecular Weight
332.35
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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