GNF-5837

Product Specifications

CAS Number

1033769-28-6

Target

PDGFR|||c-Kit|||Trk receptor

Related Pathways

Angiogenesis|||Tyrosine Kinase/Adaptors

Purity

0.9929

Bioactivity

GNF-5837 is a specific, and orally bioavailable pan-TRK inhibitor for TrkA/TrkB (IC50: 8/12 nM) .

Smiles

Cc1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)cc1Nc1ccc2\C(=C\c3ccc[nH]3)C(=O)Nc2c1

Molecular Formula

C28H21F4N5O2

Molecular Weight

535.49

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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