GNF-5837
Product Specifications
CAS Number
1033769-28-6
Target
PDGFR, c-Kit, Trk receptor
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.9929
Bioactivity
GNF-5837 is a specific, and orally bioavailable pan-TRK inhibitor for TrkA/TrkB (IC50: 8/12 nM) .
Smiles
Cc1ccc(NC(=O)Nc2cc(ccc2F)C(F)(F)F)cc1Nc1ccc2\C(=C\c3ccc[nH]3)C(=O)Nc2c1
Molecular Formula
C28H21F4N5O2
Molecular Weight
535.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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