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PDE4-IN-9

Product Specifications

CAS Number

2519450-32-7

Target

Others, PDE

Related Pathways

Metabolism, Others

Bioactivity

PDE4-IN-9 (Compound 5j) is a potent PDE4 inhibitor with an IC50 value of 1.4 μM against PDE4 in vitro enzyme assays, which is lower than the 2.0 μM of parent rolipram, and demonstrates good in vivo activity in LPS-induced animal models of asthma/COPD and sepsis [1].

Smiles

C(=O)(C=1N=C(OC1)C2=CC=C(OC)C=C2)N3\C(=N\C#N)\SCC3

Molecular Formula

C15H12N4O3S

Molecular Weight

328.35

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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