PDE4-IN-9
Product Specifications
CAS Number
2519450-32-7
Target
Others, PDE
Related Pathways
Metabolism, Others
Bioactivity
PDE4-IN-9 (Compound 5j) is a potent PDE4 inhibitor with an IC50 value of 1.4 μM against PDE4 in vitro enzyme assays, which is lower than the 2.0 μM of parent rolipram, and demonstrates good in vivo activity in LPS-induced animal models of asthma/COPD and sepsis [1].
Smiles
C(=O)(C=1N=C(OC1)C2=CC=C(OC)C=C2)N3\C(=N\C#N)\SCC3
Molecular Formula
C15H12N4O3S
Molecular Weight
328.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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