THK-5117
Product Specifications
CAS Number
1374107-54-6
Target
Microtubule Associated|||Others
Related Pathways
Others|||Cytoskeletal Signaling
Bioactivity
THK-5117 is an arylquinoline derivative with the potential as a PET probe for tau imaging. THK-5117 shows high binding affinity to tau fibrils with a Ki value of 10.5 nM. THK-5117 also shows high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD) brain homogenates [1].
Smiles
O(CC(CF)O)C1=CC2=C(N=C(C=C2)C3=CC=C(NC)C=C3)C=C1
Molecular Formula
C19H19FN2O2
Molecular Weight
326.36
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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