JAK-2/3-IN-3
Product Specifications
Target
Others|||Apoptosis|||JAK
Related Pathways
Chromatin/Epigenetic|||Angiogenesis|||Tyrosine Kinase/Adaptors|||Apoptosis|||Others|||Stem Cells|||JAK/STAT signaling
Bioactivity
JAK-2-/3-IN-3 (compound ST4j) is a potent inhibitor of JAK2/3, with IC50 values of 13.00 and 14.86 nM for JAK2 and JAK3, respectively. It inhibits JAK2 autophosphorylation, induces apoptosis in a time- and dose-dependent manner, and can be used in lymph-derived diseases and leukemia research [1].
Molecular Formula
C13H10Cl2N4O2
Molecular Weight
325.15
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/A630F4F8-0F5E-4D30-99B7-864C83464803/T60895
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
