JAK-2/3-IN-3
Product Specifications
Target
Others, Apoptosis, JAK
Related Pathways
Chromatin/Epigenetic, Angiogenesis, Tyrosine Kinase/Adaptors, Apoptosis, Others, Stem Cells, JAK/STAT signaling
Bioactivity
JAK-2-/3-IN-3 (compound ST4j) is a potent inhibitor of JAK2/3, with IC50 values of 13.00 and 14.86 nM for JAK2 and JAK3, respectively. It inhibits JAK2 autophosphorylation, induces apoptosis in a time- and dose-dependent manner, and can be used in lymph-derived diseases and leukemia research [1].
Molecular Formula
C13H10Cl2N4O2
Molecular Weight
325.15
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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