AZD 6482
Product Specifications
CAS Number
1173900-33-8
Target
Autophagy, DNA-PK, PI3K
Related Pathways
PI3K/Akt/mTOR signaling, Autophagy, DNA Damage/DNA Repair
Purity
0.9995
Bioactivity
AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values of 0.69nM and 10nM, respectively. AZD 6482 is particularly effective in blocking AKT signaling and tumor growth dependent on p110β activation or PTEN loss.
Smiles
C[C@@H](Nc1ccccc1C(O)=O)c1cc(C)cn2c1nc(cc2=O)N1CCOCC1
Molecular Formula
C22H24N4O4
Molecular Weight
408.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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