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AZD 6482

Product Specifications

CAS Number

1173900-33-8

Target

Autophagy, DNA-PK, PI3K

Related Pathways

PI3K/Akt/mTOR signaling, Autophagy, DNA Damage/DNA Repair

Purity

0.9995

Bioactivity

AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values ​​of 0.69nM and 10nM, respectively. AZD 6482 is particularly effective in blocking AKT signaling and tumor growth dependent on p110β activation or PTEN loss.

Smiles

C[C@@H](Nc1ccccc1C(O)=O)c1cc(C)cn2c1nc(cc2=O)N1CCOCC1

Molecular Formula

C22H24N4O4

Molecular Weight

408.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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