NF-?B-IN-4
Product Specifications
Target
Others|||Apoptosis|||NF-?B
Related Pathways
Others|||NF-?B|||Apoptosis
Bioactivity
NF-?B-IN-4 (compound 17) is a potent inhibitor of the NF-?B pathway that can cross the blood-brain barrier (BBB) . It exhibits potential anti-neuroinflammatory activity with low toxicity, making it suitable for researching neuroinflammation-related diseases. NF-?B-IN-4 can block I?B? activation and phosphorylation, reduce NLRP3 expression, and thereby inhibit NF-?B activation [1].
Molecular Formula
C18H15FN4O
Molecular Weight
322.34
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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