ENMD-1068 hydrochloride
Product Specifications
CAS Number
2703451-51-6
Target
Others, Protease-activated Receptor, Apoptosis
Related Pathways
GPCR/G Protein, Apoptosis, Others
Bioactivity
ENMD-1068 hydrochloride, a selective protease-activated receptor 2 (PAR2) antagonist, inhibits TGF-β1/Smad signaling, thereby reducing hepatic stellate cell activation and collagen expression. It also suppresses the proliferation of endometrial cells and triggers apoptosis in epithelial lesion cells. This compound is utilized in researching endometriosis and liver fibrosis [1] [2].
Smiles
C(CC(C)C)(=O)N1CCN(C(CCCCCN)=O)CC1.Cl
Molecular Formula
C15H30ClN3O2
Molecular Weight
319.87
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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