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PF-543

Product Specifications

CAS Number

1415562-82-1

Target

LPL Receptor, Autophagy, Apoptosis, S1P Receptor

Related Pathways

Autophagy, GPCR/G Protein, Apoptosis

Purity

0.9929

Bioactivity

PF-543 (Sphingosine Kinase 1 Inhibitor II), a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 of 2.0 nM and Ki of 3.6 nM.

Smiles

Cc1cc(CS(=O)(=O)c2ccccc2)cc(OCc2ccc(CN3CCC[C@@H]3CO)cc2)c1

Molecular Formula

C27H31NO4S

Molecular Weight

465.6

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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