PF-543
Product Specifications
CAS Number
1415562-82-1
Target
LPL Receptor|||Autophagy|||Apoptosis|||S1P Receptor
Related Pathways
Autophagy|||GPCR/G Protein|||Apoptosis
Purity
0.9929
Bioactivity
PF-543 (Sphingosine Kinase 1 Inhibitor II), a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 of 2.0 nM and Ki of 3.6 nM.
Smiles
Cc1cc(CS(=O)(=O)c2ccccc2)cc(OCc2ccc(CN3CCC[C@@H]3CO)cc2)c1
Molecular Formula
C27H31NO4S
Molecular Weight
465.6
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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MDC (Macrophage Derived Chemokine, CCL22, ABCD1, DC/B-CK, SCYA22, STCP1, Chemokine C-C-Motif Ligand 22, Small Inducible Cytokine Subfamily A (Cys-Cys) Member 22, Stimulated T-Cell Chemotactic Protein 1)
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