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Rabusertib

Product Specifications

CAS Number

911222-45-2

Target

Chk, Autophagy, PDK

Related Pathways

Cell Cycle/Checkpoint, PI3K/Akt/mTOR signaling, Autophagy

Purity

0.9987

Bioactivity

Rabusertib (IC-83) is an inhibitor of the cell cycle checkpoint kinase 1 (chk1) with potential chemopotentiating activity. Rabusertib has been used in trials studying the treatment of Cancer, Solid Tumors, Advanced Cancer, Pancreatic Neoplasms, and Non-Small Cell Lung Cancer.

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Cc1cnc(NC(=O)Nc2cc(Br)c(C)cc2OC[C@@H]2CNCCO2)cn1

Molecular Formula

C18H22BrN5O3

Molecular Weight

436.3

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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