AChE/BuChE-IN-2
Product Specifications
CAS Number
1946008-31-6
Target
Cholinesterase (ChE) |||Beta Amyloid|||Others
Related Pathways
Others|||Neuroscience
Bioactivity
AChE/BuChE-IN-2 (Compound 5f) is an orally active inhibitor of AChE and BuChE with IC50 values of 0.72 ?M and 0.16 ?M, respectively, and can cross the BBB. AChE/BuChE-IN-2 shows potent inhibition of self-induced ?-amyloid (A?) aggregation with an IC50 of 62.52 ?M and demonstrates non-competitive inhibition with AChE [1].
Smiles
C=1(C2=C(N=C(C1)C=3C=C4C(=CC3)OCO4)C=CC=C2)N5CCCC5
Molecular Formula
C20H18N2O2
Molecular Weight
318.37
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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